Reference(s):

1. Mayer, L. E., Roberto, C. A., Glasofer, D. R., Etu, S. F., Gallagher, D., Wang, J., et al. (2007). Does percent body fat predict outcome in anorexia nervosa? Am J Psychiatry, 164(6), 970-972.
2. Background Reference: Mayer, L., Walsh, B. T., Pierson, R. N., Jr., Heymsfield, S. B., Gallagher, D., Wang, J., et al. (2005). Body fat redistribution after weight gain in women with anorexia nervosa. Am J Clin Nutr, 81(6), 1286-1291.

Article(s):

1. Mayer Does percent body fat predict outcome in AN.pdf
2. Mayer Body fat redistribution after weight gain in women with anorexia nervosa.pdf

    

    

Discussion:

Another good discussion! Janelle described the Morgan-Russell criteria for outcome in AN. We discussed the first article: treatment successes (with M-R outcomes of full, good, or fair; n=16) had higher body fat percentages as measured by DEXA than treatment failures (with poor M-R outcome; n=10), despite no difference in BMI at treatment completion. Perhaps importantly, there was no mention of illness severity, as measured either by admission BMI or length of illness, which might have influenced body fat percentage.

In the background paper, Mayer et al describe different distrbutions of adipose tissue in underweight AN patients, those same patients after weight restoration, and in healthy controls. Refed patients tend to have higher truncal and intramuscular adiposity than either acutely ill AN patients or healthy controls. This is consistent with Ancel Keys' study in the 1940's with conscientious objectors who were starved and refed.

Our next journal club meeting will be MARCH 21 at NOON in the Meyer 4 activity room. As always, PLEASE let me know if there are topics/areas you are interested in, and we will work on getting them included.

Please forward the link to this page to others who may be interested in attending.

Thanks, and I look forward to continuing the discussion.

Graham